For those people with recurrent pregnancy loss or infertility, PGS applies the technology from PGD to improve their chances for a successful pregnancy. Embryos are screened for aneuploidy (missing or additional numbers of chromosomes), which is a leading cause of miscarriage and implantation failure (failure of the embryo to implant into the uterus).
The goal of PGS is to identify chromosomally abnormal embryos, so they will not be transferred leaving the chromosomally normal embryos to be transferred in the attempt to achieve a successful pregnancy.
Who should have Preimplantation Genetic Diagnosis
Preimplantation Genetic Diagnosis is an extremely useful tool for couples in which one or both of the partners are carriers of an inherited genetic disorder.
Preimplantation Genetic Diagnosis significantly reduces this risk. Preimplantation Genetic Screening, on the other hand, may only be beneficial for a specific population of patients.
This includes patients of advanced maternal age and women with a history of recurrent pregnancy loss. Patients must have a large number of good quality embryos in order for Preimplantation Genetic Screening to improve their outcome.
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